ICGC Goals, Structure, Policies and Guidelines (February 2010)

ICGC Goal: To obtain a comprehensive description of genomic, transcriptomic and epigenomic changes in 50 different tumor types and/or subtypes which are of clinical and societal importance across the globe.

ICGC Funding Members Launching Large-Scale Projects (more than 500 samples)

  1. Single funding agency; or
  2. Alliance of organizations, with a representative from a single organization within the coalition appointed to the EXEC. (See Structure, below)

To support the characterization of 500 unique cases of one cancer type or subtype to the degree of comprehensiveness described in this document, ICGC Funding Members will be required to provide the equivalent of a minimum of $10 million USD in total on such a project, distributed over 5 years, for operations (salaries, consumables, etc.), excluding overhead/indirect costs and equipment. It is recognized that some countries may have lower research costs, or may be able to provide material contributions (such as specimens) that may offset the level of commitment. Guidelines will be developed to evaluate the value of “in-kind” or lower contributions, with a general principle that the Responsibility will rest with the funding organization to ensure that the level of support will be sufficient to mount a cancer genome project that will meet the guidelines of the ICGC.

Funding agencies supporting large-scale projects can self-nominate to the ICGC Executive Committee (described below) which has the responsibility for review and approval of nominations. Funding agencies are encouraged to apply for Funding Member status as they become ready to contribute to the ICGC and adopt the Consortium’s policies and guidelines.


  1. Single funding agency; or
  2. Alliance of organizations, with a representative from a single organization within the coalition appointed to the EXEC. (See Structure, below)

To support the characterization of 500 unique cases of one cancer type or subtype to the degree of comprehensiveness described in this document, ICGC Funding Members will be required to provide the equivalent of a minimum of $20 million US in total on such a project, distributed over 5 years, for operations (salaries, consumables, etc.), excluding overhead/indirect costs and equipment. It is recognized that some countries may have lower research costs, or may be able to provide material contributions (such as specimens) that may offset the level of commitment. Guidelines will be developed to evaluate the value of “in-kind” or lower contributions, with a general principle that the responsibility will rest with the funding organization to ensure that the level of support will be sufficient to mount a cancer genome project that will meet the guidelines of the ICGC. Funding organizations, bodies or groups that want to join the ICGC as a Funding Member, can self-nominate to the ICGC Executive Committee (described below) which has the responsibility for review and approval of nominations. To become an initial ICGC Funding Member (or ICGC Founder), nominations must be received before September 1, 2008. Additional funding agencies are encouraged to become Funding Members in the future, as they become ready to contribute to the ICGC and adopt the Consortium’s policies and guidelines.

  1. Single funding agency; or
  2. Alliance of organizations, with a representative from a single organization within the coalition appointed to the EXEC. (See Structure, below)

To support the characterization of 500 unique cases of one cancer type or subtype to the degree of comprehensiveness described in this document, ICGC Funding Members will be required to provide the equivalent of a minimum of $20 million US in total on such a project, distributed over 5 years, for operations (salaries, consumables, etc,), excluding overhead/indirect costs and equipment. It is recognized that some countries may have lower research costs, or may be able to provide material contributions (such as specimens) that may offset the level of commitment. Guidelines will be developed to evaluate the value of “in-kind” or lower contributions, with a general principle that the responsibility will rest with the funding organization to ensure that the level of support will be sufficient to mount a cancer genome project that will meet the guidelines of the ICGC. Funding organizations, bodies or groups that want to join the ICGC as a Funding Member, can self-nominate to the ICGC Executive Committee (described below) which has the responsibility for review and approval of nominations. To become an initial ICGC Funding Member (or ICGC Founder), nominations must be received before September 1, 2008. Additional funding agencies are encouraged to become Funding Members in the future, as they become ready to contribute to the ICGC and adopt the Consortium’s policies and guidelines.

Last Updated on: 22 May 2012